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994. A long-term study of L-arginine supplementation (9 gday for 1 month) in patients with type 2 diabetes resulted in improved peripheral and hepatic insulin sensitivity. No changes in body weight, glycated hemoglobin, serum potassium, diastolic viagra bijwerkingen spiraaltje pressure, or heart rate were demonstrated. Systolic blood pressure decreased in the L-arginine group. In a smaller trial, oral administration of low-dose arginine similar to that ingested in a high-protein meal did not produce an increase in insulin concentration but did enhance glucagon levels. In a study of spiraalte vasodilator effects of L-arginine, co-infusion with insulin enhanced the potency of arginine with increases in renal and ocular hemodynamic parameters.

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